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Venous leg ulcers (VLU) are chronic ulcers caused by excessive venous pressure in the lower extremities and abnormal venous blood flow, eventually leading to the formation of an ulcer on the skin of the lower leg (Palfreyman et al., 2007; Chapman, 2017). It is one of the clinical manifestations of chronic venous insufficiency at the most severe stage. The underlying causes of the disease are venous valve incompetence and calf muscle pump insufficiency, leading to venous stasis and hypertension (Gianfaldoni et al., 2017). In this case, the local blood circulation is altered, and the blood supply to the local tissue is insufficient (Serra et al., 2016). Prolonged care leads to high treatment costs. Moreover, the quality of life of patients with chronic VLU is severely affected (Salome et al., 2016). Clean the wound with normal saline. In the event of prior use of an antiseptic (except contraindicated antiseptics), rinse the wound carefully with normal saline before applying the dressing.

at System.Web.Mvc.Html.PartialExtensions.Partial(HtmlHelper htmlHelper, String partialViewName, Object model, ViewDataDictionary viewData) Imanishi K., Morita K., Matsuoka M., Hayashi H., Furukawa S., Terashita F., et al.. (2006). Prevention of postoperative pressure ulcers by a polyurethane film patch. J. Dermatol. 33, 236–237. 10.1111/j.1346-8138.2006.00057.x [ PubMed] [ CrossRef] [ Google Scholar] These products should be used on specialist advice only. Tissue Viability referral must be completed prior to Venturi products being prescribed. Lázaro-Martínez JL et al. Optimal wound closure of diabetic foot ulcers with early initiation of TLC-NOSF treatment: post-hoc analysis of Explorer. J Wound Care. 2019 Jun 2; 28(6): 358-367. Morton L. M., Phillips T. J. (2012). Wound healing update. Semin. Cutan. Med. Surg. 31, 33–37. 10.1016/j.sder.2011.11.007 [ PubMed] [ CrossRef] [ Google Scholar]

Dressing retention in particular of large post-operative wound dressings, gauze and absorbent compresses. UrgoClean Ag can be cut using sterile scissors to adjust the dressing size to fit the wound if necessary. Francesko A., Petkova P., Tzanov T. (2017). Hydrogel dressings for advanced wound management. Curr. Med. Chem. 25, 5782–5797. 10.2174/0929867324666170920161246 [ PubMed] [ CrossRef] [ Google Scholar]

Clinicians/healthcare professionals should be aware that there are very limited data on prolonged and repeated use of silver containing dressings, particularly in children and neonates. Biatain ® Silicone Lite is a thin and ultra flexible foam dressing with gentle silicone adhesive. It can be used on a wide range of exuding wounds and is to be used whenever a thin foam dressing is needed. Biatain ® Silicone Lite combines superior absorption and increased mobility. dos Santos M. R., Alcaraz-Espinoza J. J., da Costa M. M., de Oliveira H. (2018). Usnic acid-loaded polyaniline/polyurethane foam wound dressing: preparation and bactericidal activity. Mater. Sci. Eng. C Mater. Biol. Appl. 89, 33–40. 10.1016/j.msec.2018.03.019 [ PubMed] [ CrossRef] [ Google Scholar] Maggio G., Armenio A., Ruccia F., Giglietto D., Pascone M., Ribatti D. (2012). A new protocol for the treatment of the chronic venous ulcers of the lower limb. Clin. Exp. Med. 12, 55–60. 10.1007/s10238-011-0136-7 [ PubMed] [ CrossRef] [ Google Scholar]

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Bernard., F.X., Barrault, C., Juchaux, F., et al.Stimulation of the proliferation of human dermal fibroblasts in vitro by a lipidocolloid dressing. J Wound Care 2005; 14: 5, 215–220. (Study conducted on UrgoTul) Park G. B. (1978). Burn wound coverings - a review. Biomater. Med. Devices Artif. Organs 6, 1–35. 10.3109/10731197809118690 [ PubMed] [ CrossRef] [ Google Scholar] Barnea Y., Weiss J., Gur E. (2010). A review of the applications of the hydrofiber dressing with silver (Aquacel Ag) in wound care. Ther. Clin. Risk Manage. 6, 21–27. 10.2147/TCRM.S3462 [ PMC free article] [ PubMed] [ CrossRef] [ Google Scholar] Broadbent E., Petrie K. J., Alley P. G., Booth R. (2003). Psychological stress impairs early wound repair following surgery. Psychosom. Med. 65, 865–869. 10.1097/01.PSY.0000088589.92699.30 [ PubMed] [ CrossRef] [ Google Scholar] Augustin M, Keuthage W, Lobmann R, Lützkendorf S, Groth H, Möller U, Thomassin L, Bohbot S, Dissemond J, Blome C. Clinical evaluation of UrgoStart Plus dressings in real-life conditions: results of a prospective multicentre study on 961 patients. J Wound Care. 2021 Dec 2;30(12):966-978. doi: 10.12968/jowc.2021.30.12.966. PMID: 34881999.

TLC-NOSF: Lipido-Colloid technology – Nano OligaSaccharide Factor (KSOS: Potassium octasulfate sucrose salt).

Norman G., Westby M. J., Rithalia A. D., Stubbs N., Soares M. O., Dumville J. C. (2018). Dressings and topical agents for treating venous leg ulcers. Cochrane Database Syst. Rev. 6:CD012583. 10.1002/14651858.CD012583.pub2 [ PMC free article] [ PubMed] [ CrossRef] [ Google Scholar] Medihoney Gel Sheet is a sterile, non-adherent wound dressing made from Medihoney Antibacterial Honey (80%w/w) and Sodium Alginate for wound care (20%w/w).